Streptomycin is an antibiotic used to treat a number of bacterial infections. This includes tuberculosis, Mycobacterium avium complex, endocarditis, brucellosis, Burkholderia infection, plague, tularemia, and rat bite fever. For active tuberculosis it is often given together with isoniazid, rifampicin, and pyrazinamide. It is given by injection into a vein or muscle.
Dihydrostreptomycin is a derivative of streptomycin that has a bactericidal properties. It is a semisynthetic aminoglycoside antibiotic used in the treatment of tuberculosis. It acts by irreversibly binding the S12 protein in the bacterial 30S ribosomal subunit, after being actively transported across the cell membrane, which interferes with the initiation complex between the mRNA and the bacterial ribosome.
The current European Maximum Residue Limit for streptomycin and dihydrostreptomycin are set at 200ug/kg in bovine milk according to EU Council Regulation EEC No.2377/90.
This product is a mouse monoclonal antibody against steptomycin and its derivative dihydrostreptomycin, which can be used in immunoassay for the detection of streptomycins in various biological samples.
ELISA, lateral flow immunoassay and other immunoassays.
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