Anti porcine Aujeszky’s disease virus monoclonal antibody / clone # 4G2-1H10

Aujeszky’s disease, usually called pseudorabies in the United States, is a viral disease in swine that has been endemic in most parts of the world. It is caused by Suid herpesvirus 1 (SuHV-1). Aujeszky’s disease is considered to be the most economically important viral disease of swine in areas where classical swine fever (hog cholera) has been eradicated.

Pseudorabies virus is a DNA herpesvirus. The pig is the only reservoir host, but the virus can infect cattle, sheep, cats, dogs, and goats as well as wildlife, including raccoons, opossums, skunks, and rodents. Experimental studies in nonhuman primates indicate that rhesus monkeys and marmosets are susceptible but chimpanzees are not. Reports of human infection are limited and are based on seroconversion rather than virus isolation. Infections in horses are rare. Only one serotype of pseudorabies virus is recognized, but strain differences have been identified using monoclonal antibody preparations, restriction endonuclease assays, and heat and trypsin inactivation markers.